Thursday, September 17, 2015

What is papillary thyroid carcinoma?

My histopatholoy read:  Well-differentiated pattern lesion with papillary cytology.  Part B shows papillary carcinoma.....

When the "bomb" was thrown to me three days ago, i read and re-read the test results, the laboratory tests, medical reports and operative report.  It says carcinoma...papillary thyroid carcinoma.  What in the world is papillary thyroid carcinoma?

 the final pathology report

  • Papillary and follicular thyroid cancers are referred to as differentiated thyroid cancer, which means that the cancer cells look and act in some respects like normal thyroid cells.
    • Papillary and follicular thyroid cancers account for more than 90% of all thyroid cancers. They tend to grow very slowly.
    • Their variants include columnardiffuse sclerosing, follicular variant of papillary, Hürthle cell, and tall cell. Two other variants (insular andsolid/trabecular) are considered to be intermediate between differentiated thyroid cancer and poorly differentiated thyroid cancer. The variants tend to grow and spread more than typical papillary cancer.
    • If detected early, most papillary and follicular thyroid cancers can be treated successfully. Their treatment and management are similar and are based on staging and individual risk levels.
    • Papillary thyroid cancer is the most common type of thyroid cancer. It accounts for about 80% of all thyroid cancers. Papillary thyroid cancer generally grows very slowly, but can often spread to lymph nodes in the neck. It also can spread elsewhere in the body.
    • The most common variant of papillary is the follicular variant (not to be confused with follicular thyroid cancer). It also usually grows very slowly. Other variants of papillary thyroid cancer (columnar, diffuse sclerosing, and tall cell) are not as common and tend to grow and spread more quickly.
    • Follicular thyroid cancer accounts for about 10-15% of all thyroid cancers. Treatment will be discussed later in this booklet. Hürthle cell thyroid cancer is a variant of follicular.
    • Follicular thyroid cancers usually do not spread to the lymph nodes, but in some cases can spread to other parts of the body, such as the lungs or bones.
    • Treatment for follicular thyroid cancer is similar to treatment for papillary. Hürthle cell cancer (also known as oncocytic or oxyphilic) is less likely than other differentiated thyroid cancer to absorb radioactive iodine, which is often used for the treatment of differentiated thyroid cancer.
    • A protein called thyroglobulin (abbreviated Tg) is used as a marker for whether all of the differentiated thyroid cancer has been successfully removed. Determining the Tg level in your blood by periodic testing will help your doctors determine how well you are doing with your treatment. Some patients produce anti-thyroglobulin antibodies (TgAb), which are not harmful but which mask the reliability of the Tg value.
Cancer of any type is still cancer - scary and dreadful.  A lot of doctors say, even my doctor, that thyroid carcinoma is the simpliest and the easiest to treat.  Well, it is still cancer, right?

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